Objective: To set up a method for the determination of the content of bacterial endotoxin in saline injection of ligustrazine phosphate.
目的：建立磷酸川芎嗪氯化钠注射液中细菌内毒素含量测定方法。OBJECTIVE To investigate the characteristics of nasal mucosa absorption of ligustrazine phosphate and its pharmacokinetics.
目的研究磷酸川芎嗪的鼻黏膜吸收特性及体内药动学。Methods: To explore the influences of the different extraction, concentration and drying method on the transferring rate of TMP by HPLC.
方法：用HPLC法考察不同的提取、浓缩及干燥方法对川芎嗪的提取率及转移率的影响。Objective: To determine the content of Ligustrazine Phosphate freezing - drying powder for Injection.
目的：研究注射用磷酸川芎嗪冻干粉针剂含量检测。Objective: To investigate the apoptosis effect and mechanism of action of ligustrazine against cisplatin-induced ototoxicity.
目的：探讨川芎嗪对顺铂耳蜗毒性中细胞凋亡的影响及可能的作用机制。Objective: The kinetic turbidimetric Limulus test was used in the endotoxin assay of Ligustrazin Hydrochloride injection.
目的：应用动态比浊法鲎试验定量测定盐酸川芎嗪注射液中的细菌内毒素含量。Objective To explore the relationship between functional constipation and medium molecular substance.
目的研究大黄素、川芎嗪对中分子物质引起大脑皮层神经元损伤的保护作用。Objective To observe the expression of induced nitric oxide synthase in ligustrazine against cisplatin-induced ototoxicity.
目的观察诱导型一氧化氮合酶在川芎嗪拮抗顺铂耳毒性作用中的表达情况。Conclusion: Ligustrazine combining mecobalamine injection can relieve the clinical symptoms of the patients with DPN more effectively.
结论：川芎嗪联合甲钴胺能够更有效减轻DPN患者的临床症状。