METHODS Cilnidipine was synthesized from cinnamyl alcohol by esterification, feminization and condensation - cyclization.
方法以肉桂醇为原料,经酯化 、 氨化和缩合 - 环合而得.
Levocetirizine Dihydrochloride was prepared from benzoyl chloride by acidylation, hydrogenation, cyclization with an overall yield of 8.05 %.
以苯甲酰氯为原料,经酰化, 还原, 环合等反应合成左旋西替利嗪盐酸盐,反应总收率为8.05%.
The effect of solvents and steric hindrance on the stereochemistry of cyclization is investigated in details.
并且考察了在环合反应中溶剂和空间位阻对立体选择性的影响.
Methods: Simvastatin was synthesized from lovastatin via acetylization, methylation, hydrolytic decomposition and cyclization reactions.
方法: 以洛伐他汀为原料,通过酰化 、 甲基化 、 水解、环合等反应合成了辛伐他汀.
Methods: The compound was synthesize by steps of reduction, condensation and cyclic condensation from 1, 2 - dicyanocyclobutane.
方法以1, 2- 二氰基环丁烷为原料,经还原 、 缩合、环合三步反应得到洛铂.
Methods: Starting from diethanolamine, BP 897 was prepared via chlorination, cyclization, substitution aminolysis and condensation reaction.
方法: 以二羟乙基胺为起始原料, 经过氯化 、 环合 、 取代、肼解、缩合等反应合成BP897.
Methods: The target compound was synthesized through bromination and thioetherification from 4 - methoxyacetophenone as a starting material.
方法以3-甲氧基苯硫酚和对甲氧基 - 苯乙酮为原料经溴化、烃基化、环合重排排制得目标产物.
Sodium ethylate was used as catalyst in Baker - Venkataraman of cyclization, and all factors were studied.
环合反应采用乙醇钠作为Baker-Venkataraman重排反应的催化剂, 研究了影响反应的各个因素.